ARA-290 – Research-Grade Erythropoietin-Derived Peptide (Helix B Fragment)

ARA-290, also known as cibinetide, is a synthetic peptide derived from the helix B region of erythropoietin (EPO). Unlike full-length erythropoietin, ARA-290 consists of a short, non-erythropoietic amino acid sequence designed to preserve selective structural features of the parent molecule while eliminating hematopoietic activity. In laboratory research settings, ARA-290 is utilized to investigate EPO-derived signaling motifs, peptide–receptor interaction models, and structure–function relationships associated with helix B–specific domains.

Due to its truncated structure, ARA-290 does not activate classical erythropoietin receptors responsible for red blood cell production in vitro. This functional distinction allows researchers to isolate and examine non-hematopoietic signaling pathways and receptor interactions associated with EPO-derived peptides. Its defined sequence and synthetic consistency make ARA-290 a valuable research tool for mechanistic studies, intracellular signaling analysis, and peptide-based biochemical exploration conducted under controlled laboratory conditions.

Related research compounds

KPV · LL-37 · Thymosin Alpha-1 · Thymalin · BPC-157

Documentation and methods

Analytical testing · How to read a COA · Batch COAs · Storage and handling · What are research peptides

Important Information About This Research Product

1. 1 Your vials are not empty. The lyophilized material may collect at the bottom of the vial and can appear minimal prior to inspection.
2. 2 All products are supplied as lyophilized (freeze-dried) powder and require reconstitution. Bacteriostatic water is not supplied.
3. 3 Store in a dry, cool, and dark environment away from UV exposure. For optimal preservation, storage at approximately 4°C is recommended.
4. 4 This material is strictly for laboratory and research use only. No instructions regarding reconstitution, dosing, or administration can be provided.