LL-37 – Research-Grade Human Cathelicidin Antimicrobial Peptide

LL-37 is a synthetic research analog of the human cathelicidin antimicrobial peptide, comprising 37 amino acid residues derived from the C-terminal region of the hCAP-18 precursor protein. This peptide has been extensively described in scientific literature for its distinctive cationic and amphipathic properties. In laboratory research settings, LL-37 is utilized as a reference material for studying peptide–membrane interactions, innate immune signaling models, and sequence-dependent antimicrobial mechanisms.

Due to its linear structure and absence of disulfide bonds, LL-37 exhibits conformational flexibility that differentiates it from cyclic peptides and larger protein-based immune factors. This characteristic allows researchers to investigate membrane association, peptide-induced structural changes, and degradation behavior in vitro. Its defined amino acid sequence and reproducible synthesis support consistent use in mechanistic assays, comparative peptide studies, and exploratory biochemical research conducted under controlled laboratory conditions.

Related research compounds

KPV · Thymosin Alpha-1 · Thymalin · ARA-290 · BPC-157 + TB-500 + GHK-Cu + KPV (KLOW Blend)

Documentation and methods

Analytical testing · How to read a COA · Batch COAs · Storage and handling · What are research peptides

Important Information About This Research Product

1. 1 Your vials are not empty. The lyophilized material may collect at the bottom of the vial and can appear minimal prior to inspection.
2. 2 All products are supplied as lyophilized (freeze-dried) powder and require reconstitution. Bacteriostatic water is not supplied.
3. 3 Store in a dry, cool, and dark environment away from UV exposure. For optimal preservation, storage at approximately 4°C is recommended.
4. 4 This material is strictly for laboratory and research use only. No instructions regarding reconstitution, dosing, or administration can be provided.