ACE-031 – Research-Grade Recombinant Fusion Protein

ACE-031 is a recombinant fusion protein composed of the extracellular domain of Activin Receptor Type IIB (ActRIIB) linked to the Fc region of human IgG1. This engineered construct forms a disulfide-linked dimer and is structurally distinct from short synthetic peptides or full-length endogenous receptors.

In laboratory research settings, ACE-031 is utilized as a reference material for studying ligand–receptor interaction models, extracellular domain binding dynamics, and structure–function relationships within TGF-β superfamily signaling pathways. The fusion design enables controlled investigation of receptor-domain behavior in vitro.

Unlike small peptide constructs, ACE-031 represents a higher-order biologic system that may exhibit domain-level folding and post-translational modification depending on expression conditions. This material is intended strictly for laboratory research use only and is not designed for human or veterinary application.

Related research compounds

Follistatin 344 · IGF-1 LR3 · Ipamorelin · CJC-1295 (No DAC) · Sermorelin

Documentation and methods

Analytical testing · How to read a COA · Batch COAs · Storage and handling · What are research peptides

Important Information About This Research Product

1. 1 Your vials are not empty. The lyophilized material may collect at the bottom of the vial and can appear minimal prior to inspection.
2. 2 All products are supplied as lyophilized (freeze-dried) powder and require reconstitution. Bacteriostatic water is not supplied.
3. 3 Store in a dry, cool, and dark environment away from UV exposure. For optimal preservation, storage at approximately 4°C is recommended.
4. 4 This material is strictly for laboratory and research use only. No instructions regarding reconstitution, dosing, or administration can be provided.